Plain English Meaning
The speed the pilot aims to fly at while lined up to land. It is fast enough to keep the airplane safely above stalling, but slow enough to touch down where intended.
Full Definition
The airspeed flown during the final approach segment of a landing, set above the airplane's stall speed in landing configuration by a margin specified in the Pilot's Operating Handbook (POH) or Airplane Flight Manual (AFM). It is typically expressed as a multiple of Vso (stall speed in landing configuration) — commonly 1.3 Vso — and may be adjusted for gust factor, weight, or flap setting as the manufacturer directs.