Plain English Meaning

Drugs or substances that slow your brain and body down. They can make you drowsy, less alert, slower to react, and less able to think clearly — all things that are dangerous in the cockpit.

Full Definition

Depressants are drugs that slow the central nervous system, reducing brain activity and producing effects such as sedation, impaired judgment, slowed reaction time, and reduced coordination. Common examples include alcohol, antihistamines, sleeping pills, and certain anti-anxiety medications. Many depressants are disqualifying for flight either by FAA regulation or by their effect on pilot performance.

Context Anchor

Seen in aeromedical and drug-use discussions, especially when deciding whether a medicine or substance is safe before flying.