Plain English Meaning
A point on a GPS route that you have to fly directly over the top of before you start turning toward the next point. No early turns allowed.
Full Definition
Fly-over waypoints are GPS waypoints that the aircraft must pass directly over before initiating any turn to the next leg of the route. The navigation system does not anticipate or cut the corner; it holds the current course until the aircraft is over the waypoint, then commands the turn.
Context Anchor
Seen on GPS instrument approach procedures and in the GPS flight plan where certain waypoints control exactly when the aircraft may turn.