Plain English Meaning
The airplane is heavier on one side than the other, so it wants to roll toward the heavy side and the pilot has to hold the controls against it.
Full Definition
A loading state in which the aircraft's weight is distributed unevenly between the left and right sides of the longitudinal axis, causing one wing to carry more weight than the other. This produces a rolling tendency that the pilot must counter with aileron input, increasing drag and reducing performance.
Context Anchor
Seen in weight-and-balance discussions, especially when loading passengers, baggage, or unevenly between the left and right sides of the aircraft.