Plain English Meaning
Everything the pilot does before flying to make sure the aircraft, equipment, paperwork, and plan are all ready to go.
Full Definition
The set of checks, inspections, and preparations a pilot completes before flight to confirm that the aircraft, its systems, the route, weather, performance, and required documents are all ready and legal for the planned flight. For instrument operations, this includes verifying that navigation systems and avionics are operating correctly and that current databases and charts are on board.
Context Anchor
Seen in systems preflight procedures, especially before an instrument flight, when the pilot verifies that the required navigation instruments and systems are working and suitable for the planned route.